Ibuprofen Lysine for Injection 10 mg/mL Single Use Vial 2 mL x 3 VialsIbuprofen Lysine for Injection 10 mg mL Single Use Vial 2 mL x 3 Vials. Ibuprofen Lysine is indicated to close a clinically significant patent ductus arteriosus (PDA) in premature infants weighing between 500 and 1500 g, who are no more than 32 weeks gestational age when usual medical management (e. g., fluid restriction, diuretics, respiratory support, etc.) is ineffective. The clinical trial was conducted among infants with an asymptomatic PDA.