Promethegan Promethazine HCL Suppositories 25 mg, 12 Count **Refrigerated (Rx)Promethegan Promethazine HCL Suppositories 25 mg are used to treat nausea, vomiting, and allergies. They are also effective for sedation before and after surgery, motion sickness relief, and as a sleep aid. As an antihistamine, promethazine blocks histamine receptors, helping reduce allergy symptoms like itching and runny nose. This formulation is beneficial for patients who cannot take oral medication due to nausea or vomiting. Experience relief with